Endocrine Abstracts

Introduction: Testosterone (T) improves muscle strength in hypogondal men. It is unclear if testosterone has similar effects in prefrail and frail elderly men with low T. We conducted a randomised double-blind placebo-controlled parallel group study to determine the effects of T on muscle mass and strength, physical function and quality of life in prefrail and frail elderly men.Methods: Two hundred and sixty two prefrail and frail elderly men (Fried e...

Ageing is associated with sarcopenia, osteoporosis and an increased risk of falling, which together contribute to increased fracture risk. There are few data describing the associations between functional measures of muscle and bone during ageing. Therefore, the aim of this study was to examine in ageing men associations between measures of lower-limb muscle strength and age and then to investigate the relationships with tibial bone outcomes.Men (n</...